NEWS RELEASE

Presstek Announces Information Regarding First Quarter 2008 Financial Results

Hudson, NH – May 7, 2008 – Presstek Inc. (Nasdaq: PRST), the leading manufacturer and marketer of digital offset printing business solutions, today announced it will release its first quarter 2008 financial results before the market opens on Friday, May 9, 2008. The company also announced that it expects to file its first quarter 2008 10-Q with the Securities and Exchange Commission during the week of May 12, 2008.

Presstek senior management will host a conference call on May 9, 2008 at 8:30 AM Eastern Standard Time to discuss its first quarter 2008 results. The call will be open to all interested parties and may be accessed by using the following information:

CONFERENCE CALL ACCESS
Domestic Dial In: (866) 711-8198
International Dial In: (617) 597-5327
Passcode: 80852180

Investors can access the call in a “listen only” mode via the Internet at http://www.presstek.com.

In addition, for those unable to participate at the time of the call, a rebroadcast will be available following the call from Friday, May 9, 2008 at 10:30 AM Eastern Standard Time until Friday May 17, 2008 Eastern Standard Time at midnight. The rebroadcast may be accessed on the Internet at http://www.pressstek.com or by telephone using the following information:

REBROADCAST ACCESS
Domestic Dial In: 888-286-8010
International Dial In: 617-801-6888
Passcode: 10583571

About Presstek
Presstek, Inc. is the leading manufacturer and marketer of high tech digital imaging solutions to the graphic arts and laser imaging markets. Presstek’s patented DI®, CTP and plate products provide a streamlined workflow in a chemistry-free environment, thereby reducing printing cycle time and lowering production costs. Presstek solutions are designed to make it easier for printers to cost effectively meet increasing customer demand for high-quality, shorter print runs and faster turnaround while providing improved profit margins. Presstek subsidiary, Lasertel, Inc., manufactures semiconductor laser diodes for Presstek’s and external customers’ applications. For more information visit www.presstek.com, or call 603-595-7000 or email: info@presstek.com.

DI is a registered trademark of Presstek, Inc.

CONTACTS:
Investor Relations
Kathleen Makrakis
Director of Investor Relations
203-485-7534 ext. 1432
kmakrakis@presstek.com
Trade Relations
Betty LaBaugh
Publich Relations Manager
603-594-8585 ext. 3441
blabaugh@presstek.com


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